IBBR Project #112
NEMATIC - Materiali Nanoporosi: Lavagne Autoassemblanti per lo Studio della Struttura e delle Interazioni del DNA
| Project ID | 112 |
| ID | n/a |
| Acronym | - |
| Project acronym and title | NEMATIC - Materiali Nanoporosi: Lavagne Autoassemblanti per lo Studio della Struttura e delle Interazioni del DNA |
| Contract | - |
| Description | NEMATIC is a highly multidisciplinarity project integrating biochemistry and molecular biology, biophysics, chemistry and molecular dynamics, with the aim to develop nanopore-based microarray devices for the study of DNA structure, topology and interaction with proteins. Protein-induced DNA structure and topology modifications are crucial in all DNA activities. Self-assembled nano- and mesoporous material will be fabricated and used to set up nanopores to study, through the analysis of the nucleic acid electrically driven nanopore translocation, DNA structural modifications induced by selected thermophilic and mesophilic DNA-acting proteins. Nanopore-based innovative microsystems will enhance laboratory practice by permitting spatial and temporal analytical resolution of DNA structure modifications and DNA-protein interactions down to the single-molecule level. Other partners: - Dipartimento di Fisica Università di Trento - Istituto di Chimica del Riconoscimento Molecolare (ICRM), CNR, Milano - Istituto dei Processi Chimico-fisici (IPCF), CNR, Roma |
| Funding body | MIUR-FIRB |
| UOS | Napoli |
| Role | Research Unit |
| Signatory | - |
| Contact Person | Valenti Anna |
| Starting of activities | 2013 |
| Ending of activities | 2016 |
| Extension | - |
| Amount (euro) | 204000.00 |
| Technological Area | - |
| Technological Field | - |
