Maria Stefania Grillo
Role: Senior Researcher
Section: Researchers and Technologists
Division: Portici
Tel: (39) 081-2539213
E-mail: stefania.grillo@ibbr.cnr.it
Current appointment: Head of the Portici Division of the IBBR/CNR.
Born: | Naples (Italy), September 12 1957 |
Professional Address: | Institute of Biosciences and Bioresources, UOS PorticiVia Università 13380055 Portici (Italy) |
Job position: | Principal Investigator/CNR Senior Researcher |
Training and Professional Carreer (2013-1980)
Oct 2013 | Head of IBBR UOS Portici |
Dic 2002-Nov 2010 | Head of IGV UOS Portici |
Jan 2002 | Senior Scientist of the CNR- Plant Genetics Institute, UOS Portici |
Oct 1995- 2000 | Contract adjunct Professor at the University of Salerno and at the University of Naples ‘Federico II’ |
Jul 1991-Nov 1992 | Research Fellow at University of North Carolina at Chapel Hill NC, US |
June 1990 | Visiting Scientist at Purdue University, West Lafayette Indiana, US |
1986 | Researcher at CNR - Institute of Plant Breeding for Vegetables and Flowers, Portici |
March 1982-1984 | Research fellow of the Accademia Nazionale dei Lincei at the University of Naples, Faculty of Agriculture |
Jan 1980 | Graduated in Biology, magna cum laude, at University of Naples Federico II |
Current projects
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MiUR PON02- /GenoPOM.PRO, Potenziamento della filiera pomodoro attraverso l’uso di piattaforme integrate di post-genomica (2012-2015). Scientific Coordinator of the CNR -DISBA Partner , Member of the Managment commitee of The Project
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MiUR PON02/GenHORT, Valorizzazione di produzioni ortive campane di eccellenza con strumenti di genomica avanzata (2012-2015). Scientific Coordinator of the CNR -DISBA Partner , Member of the Management commitee of the project
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MEF-CNR CISIA - Conoscenze Integrate per la Sostenibilità e l’Innovazione del made in Italy Agroalimentare, PI IGV Portici Unit -OR 4.1
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Regione Campania PSR 2007-2013 Misura 214 Azione f2 “Salvaguardia della biodiversità vegetale della Campania” (SALVE) (2010-2015), Project participant
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Progetto Fondazione con il Sud “Produzione di dolcificanti ipocalorici da piante mediterranee” (2013-2016), PI IBBR UOS Portici Unit
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Regione Campania CAMPUS QUARC ”Qualità delle produzioni tipiche campane e il suo territorio: approci innovativi e integrati per rafforzare la competività del sistema agroalimentare” (2013-2015), PI IGV Portici Unit
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MIUR CLUSTER Tecnologico Nazionale CL.A.N., area applicativa AgriFood, “Nuove tecnologie abilitanti per la food safety e l’integrità delle filiere agro-alimentari in uno scenario globale” (Safe&Smart) (2013-2015), PI IBBR UOS Portici Unit
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Regione Campania Rete CARINA - Sicurezza, Sostenibilità e Competitività delle produzioni agroalimentari della Campania (2012-2014), Coordinator of CNR DISBA Activities
Recent Scientific Activities
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Member of the Scientific committee of The Italian Platform ‘Plant for the Future’ (IT-Plant),
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CNR elected Member of ESF -European Networking Summer School on Plant Genomics and Bioinformatics
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Member of Management Commitee alla COST Action FA0605 - Signaling control of stress tolerance and production of stress protective compounds in plants (INPAS)
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Ad Hoc Reviewer for 10 scientific journals
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Reviewer of national (MIUR, MIPAF, CNR) and international projects ( NSF, Hungarian Academy of Sciences, Israel Science and Technology Ministry)
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Invited speaker and chairperson at international and national congresses
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Teaching in National (University) and international theretical and pratical courses
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Advisor and supervisor of national and international undergraduate students, PhD students and Post Doc.
Research Interest
My research group has long experience on the applications of biotechnologies to plant breeding of vegetables crops. Research activities are focused on the identification, characterization and transfer of genes involved in the plant response to environmental stresses. We are using functional genomics approaches in Solanacee and Arabidopsis through large scale transcriptome analyses in response to osmotic and temperature stress, and characterization of crucial gene functions by means of forward and reverse genetics approaches. I am also involved in the development of molecular and biotech tools for the use of plant as biofactories for the production of bio-molecules of industrial value.
Recent Publications
Fasano R, Gonzalez N, Tosco A, Dal Piaz F, Docimo T, Serrano R, Grillo S, Leone A , Inze S 2014. Role of Arabidopsis UV RESISTANCE LOCUS 8 in Plant Growth Reduction under Osmotic Stress and Low Levels of UV-B. Molecular Plant 7. Pag.773-791 ISSN:1674-2052
Batelli G, Massarelli I, Van Oosten M, Nurcato R, Vannini C, Raimondi G, Leone A, Zhu J-K, Maggio A, Grillo S. 2012 Asg1 is a stress-inducible gene which increases stomatal resistance in salt stressed potato. Journal of Plant Physiology 169, pages 1849-1857. doi: 10.1016/j.jplph.2012.07.004.
Ambrosone A, Di Giacomo M, Leone A, Grillo S, Costa A. 2013 Identification of early induced genes upon water deficit in potato cell cultures by cDNA-AFLP. Journal of Plant Research 126: 169-178
Gargano D, Scotti N, Vezzi A, Bilardi A, Valle G, Grillo S, Cozzolino S, Cardi T. 2012 Genome-wide analysis of plastome sequence variation and development of plastidial CAPS markers in common potato and related Solanum species . Genetic Resources and Crop Evolution, 59, 419-430, ISSN: 0925-9864
Ambrosone A, Costa A, Leone A, Grillo S 2012 Beyond transcription: RNA-binding proteins as emerging regulators of plant response to environmental constraints. Plant Science 182: 12-18
Ambrosone A, Costa A, Martinelli R, Massarelli I, De Simone V, Grillo S, Leone A, 2011 Differential gene regulation in potato cells and plants upon abrupt or gradual exposure to water stress Acta Physiol Plant 33: 1157-1171
Iovieno P, Nurcato R, Massarelli I, Leone A, Grillo S. 2010 Production of tomato transgenic plants for the functional analysis of the transcription factor Hsfa2 gene in response to heat stress Minerva Biotech suppl 1 N. 2: 38-39
Giorno F, Wolters-Arts M, Grillo S, Scharf .D, Vriezen WH, Mariani C. 2010 Developmental and heat stress-regulated expression of HsfA2 and small heat shock proteinsin tomato anthers. J Exp Bot;61(2):453-462
Costa A, Di Giacomo M, Massarelli I, De Palma M, Leone A, Grillo S. 2010 Isolation and characterization of a water stress-induced elongation factor 1 alpha from Solanum tuberosum Plant s Biosystems 144 (3): 618-625
Valkov VT, Scotti N, Kahlau S, MacLean D, Grillo S, Gray JC, Bock R, Cardi T 2009 Genome-wide analysis of plastid gene expression in potato leaf chloroplasts and tuber amyloplasts: transcriptional and post-transcriptional control. Plant Physiology 150: 2030-2044
Scotti N, Alagna F, Ferraiolo E, Formisano G, Sannino L, Buonaguro L, De Stradis A, Vitale A, Monti L, Grillo S, Buonaguro FM, Cardi T. 2009 High level expression of the HIV-1 Pr55gag polyprotein in transgenic tobacco chloroplasts. Planta:1109-22.
Selected Publications
(full list available at CNR People)
Electromagnetic water enhanced metabolism and agro-physiological responses of potato (Solanum tuberosum L) under saline conditions
Akrimi R, Hajlaoui H, Batelli G, Ruggiero A, Badri M, Grillo S, Mhamdi M
Year: 2020
Physiological basis of salt stress tolerance in a landrace and a commercial variety of Sweet Pepper (Capsicum annuum L.)
Giorio P, Cirillo V, Caramante M, Oliva M, Guida G, Venezia A, Grillo S, Maggio A, Albrizio R
Year: 2020
Alternative splicing in plant abiotic stress responses
Punzo P, Grillo S, Batelli G
Year: 2020
TOMRES: identifying tomato varieties with higher resource use efficiency
Ruggiero A, Cirillo V, Batelli G, Van Oosten MJ, Costa A, Grillo S, Maggio A
Year: 2019
Preliminary study of the effect of bacterial inoculation on the response of Lycium species under saline condition
Tedeschi A, Aurilia V, Grillo MS, Nurcato R, Huang C, Jing P, Xue X
Year: 2019
Physiological, biochemical and molecular responses to water stress and re-hydration in Mediterranean adapted tomato landraces
Giorio P, Guida G, Mistretta C, Sellami MH, Oliva M, Punzo P, Iovieno P, Arena C, De Maio A, Grillo S, Albrizio R
Year: 2018
Response mechanisms induced by exposure to high temperature in anthers from thermo-tolerant and thermo-sensitive tomato plants: A proteomic perspective
Mazzeo MF, Cacace G, Iovieno P, Massarelli I, Grillo S, Siciliano RA
Year: 2018
TIP41 network analysis and mutant phenotypes predict interactions between the TOR and ABA pathways
Punzo P, Ruggiero A, Grillo S, Batelli G
Year: 2018
The PP2A-interactor TIP41 modulates ABA responses in Arabidopsis thaliana
Punzo P, Ruggiero A, Possenti M, Nurcato R, Costa A, Morelli G, Grillo S, Batelli G
Year: 2018
TOMRES: screening of traditional tomato varieties for water use efficiency and nutrient use efficiency
Ruggiero A, Batelli G, Van Oosten MJ, Costa A, Grillo S, Maggio A
Year: 2018
Chloroplast-to-nucleus communication in response to drought in tomato
Tamburino R, Castiglia D, Sannino L, Guida G, Giorio P, Albrizio R, Grillo MS, Costa A, Scotti N
Year: 2018
Distinct gene networks drive differential response to abrupt or gradual water deficit in potato
Ambrosone A, Batelli G, Bostan H, D’agostino N, Chiusano ML, Perrotta G, Leone A, Grillo S, Costa A
Year: 2017
Living in harsh environments: what we have learnt from comparing plant acclimation versus shock response to osmo-stress
Ambrosone A, Costa A, Grillo S, Leone A
Year: 2017
G6PDH expression and activity correlates with drought tolerance in a long shelf life tomato landrace
Landi S, Ruggiero A, Nurcato R, De Lillo A, Batelli G, Grillo S, Esposito S
Year: 2017
An integrated study of morphophysiological and molecular responses to combined salt/low nutrient stress of long storage tomato landraces
Ruggiero A, Batelli G, Venezia A, Lupini A, Ruggiero M, Nurcato R, Costa A, Van Oosten MJ, Palombieri S, Vitiello A, Abenavoli MR, Cammareri M, Sunseri F, Grandillo S, Grillo S
Year: 2017
Improving plant water use efficiency through molecular genetics
Ruggiero A, Punzo P, Landi S, Costa A, Van Oosten M, Grillo S
Year: 2017
Chloroplast proteome response to drought stress and recovery in tomato (Solanum lycopersicum L.)
Tamburino R, Vitale M, Ruggiero A, Sassi M, Sannino L, Arena S, Costa A, Batelli G, Zambrano N, Scaloni A, Grillo S, Scotti N
Year: 2017
Transcriptomic changes drive physiological responses to progressive drought stress and rehydration in tomato
Iovieno P, Punzo P, Guida G, Mistretta C, Van Oosten MJ, Nurcato R, Bostan H, Colantuono C, Costa A, Bagnaresi P, Chiusano ML, Albrizio R, Giorio P, Batelli G, Grillo S
Year: 2016
Glucose-6-phosphate dehydrogenase plays a central role in the response of tomato (Solanum lycopersicum) plants to short and long-term drought
Landi S, Nurcato R, De Lillo A, Lentini M, Grillo S, Esposito S
Year: 2016
Identification of pepper ABA core signaling components and their role in seed germination
Ruggiero A, Landi S, Nurcato R, Costa A, Van Oosten M, Grillo S, Batelli G
Year: 2016
Genetics of drought stress tolerance in crop plants
Van Oosten MJ, Costa A, Punzo P, Landi S, Ruggiero A, Batelli G, Grillo S
Year: 2016
The Arabidopsis AtRGGA RNA binding protein regulates tolerance to salt and drought stress.
Ambrosone A, Batelli G, Nurcato R, Aurilia V, Punzo P, Bangarusamy DK, Ruberti I, Sassi M, Leone A, Costa A, Grillo S
Year: 2015
EMS mutagenised population of Eutrema salsugineum: a new tool to discover mechanisms of tolerance to extreme environment
Ruggiero A, Nurcato R, Costa A, Aurilia V, Van Oosten M, De Palma M, Grillo S, Batelli G
Year: 2015
La cellula vegetale e i suoi genomi
Cardi T, Aversano R, D’Agostino N, Grillo S, Leone A, Scossa F, Scotti N
Year: 2014
Role of arabidopsis UV resistance locus 8 in plant growth reduction under osmotic stress and low levels of UV-B
Fasano R, Gonzalez N, Tosco A, Dal Piaz F, Docimo T, Serrano R, Grillo S, Leone A, Inze D
Year: 2014
Meccanismi molecolari della risposta a stress abiotici e aumento della tolleranza nelle piante
Grillo MS, Leone A
Year: 2014
Identification of early induced genes upon water deficit in potato cell cultures by cDNA-AFLP
Ambrosone A, Di Giacomo M, Leone A, Grillo MS, Costa A
Year: 2013
Microsatellite and morpho-agronomic polymorphisms in eggplant and pepper: genotyping and identification of traditional cultivars
Tranchida-Lombardo V, Spigno P, Riccardi R, De Palma M, Nunziata A, Nurcato R, Grillo S, Tucci M
Year: 2013
Beyond transcription: RNA-binding proteins as emerging regulators of plant response to environmental constraints
Ambrosone A, Costa A, Leone A, Grillo S
Year: 2012
Asg1 is a stress-inducible gene which increases stomatal resistance in salt stressed potato
Batelli G, Massarelli I, Van Oosten M, Nurcato R, Vannini C, Raimondi G, Leone A, Zhu J-k, Maggio A, Grillo S
Year: 2012
Asg1 is a stress-inducible gene which increases stomatal resistance in salt stressed potato
Batelli G, Massarelli I, Van Oosten M, Nurcato R, Vannini C, Raimondi G, Leone A, Zhu JK, Maggio A, Grillo S
Year: 2012
Asg1 is a stress-inducible gene which increases stomatal resistance in salt stressed potato
Batelli G, Massarelli I, Van Oosten M, Nurcato R, Vannini C, Raimondi G, Leone A, Zhu JK, Maggio A, Grillo S
Year: 2012
Genome-wide analysis of plastome sequence variation and development of plastidial CAPS markers in common potato and related Solanum species
Gargano D, Scotti N, Vezzi A, Bilardi A, Valle G, Grillo S, Cozzolino S, Cardi T
Year: 2012
Differential gene regulation in potato cells and plants upon abrupt or gradual exposure to water stress.
Ambrosone A, Costa A, Martinelli M, Massarelli I, De Simone V, Grillo S, Leone A
Year: 2011
La genomica del pomodoro
Monti L, Grillo S
Year: 2010
La pianta come biofabbrica per la produzione di prodotti naturali e proteine eterologhe di interesse farmaceutico
Leone A., Scotti N., Grillo S., Monti L., Cardi T.
Year: 2009
High-level expression of the HIV-1 Pr55gag polyprotein in transgenic tobacco chloroplasts
Scotti N, Alagna F, Ferraiolo E, Formisano G, Sannino L, Buonaguro L, De Stradis A, Vitale A, Monti L, Grillo S, Buonaguro FM, Cardi T
Year: 2009
Genome-Wide Analysis of Plastid Gene Expression in Potato Leaf Chloroplasts and Tuber Amyloplasts: Transcriptional and Posttranscriptional Control
Valkov VT, Scotti N, Kahlau S, Maclean D, Grillo S, Gray JC, Bock R, Cardi T
Year: 2009
Transplastomic tobacco plants expressing a fatty acid desaturase gene exhibit altered fatty acid profiles and improved cold tolerance
Craig W, Lenzi P, Scotti N, De Palma M, Saggese P, Carbone V, Mcgrath Curran N, Magee AM, Medgyesy P, Kavanagh TA, Dix PJ, Grillo S, Cardi T
Year: 2008
Translational fusion of chloroplast-expressed human papillomavirus type 16 L1 capsid protein enhances antigen accumulation in transplastomic tobacco
Lenzi P, Scotti N, Alagna F, Tornesello ML, Pompa A, Vitale A, De Stradis A, Monti L, Grillo S, Buonaguro FM, Maliga P, Cardi T
Year: 2008
SOS2 Promotes Salt Tolerance in Part by Interacting with the Vacuolar H -ATPase and Upregulating Its Transport Activity
Batelli G, Verslues PE, Agius F, Qiu Q, Fujii H, Pan S, Schumaker KS, Grillo S, Zhu JK
Year: 2007
Molecular tailoring and boosting of bioactive secondary metabolites in medicinal plants
Leone A, Grillo S, Monti L, Cardi T
Year: 2007
Interaction of SOS2 with Nucleoside Diphosphate Kinase 2 and Catalases Reveals a Point of Connection between Salt Stress and H2O2 Signaling in Arabidopsis thaliana
Verslues PE, Batelli G, Grillo S, Agius F, Kim YS, Zhu J, Agarwal M, Katiyar-Agarwal S, Zhu JK
Year: 2007
Functional screening of plant stress related cDNAs by random over-expression in Escherichia coli.
Massarelli I; Cioffi R; Batelli G; De Palma M; Costa A; Grillo S; Leone A
Year: 2006
Salt tolerance: Placing advances in molecular genetics into a physiological and agronomic context
Maggio A, Bressan AR, Ruggiero C, Xiong L, Grillo S
Year: 2003
Unravelling the genetic basis of drought tolerance in crops
Tuberosa R, Grillo S, Ellis RP
Year: 2003