Score: 6.09
#85 - Biofortification and plant molecular farming: two sides of the same coin
Metabolic engineering has revolutionized classic breeding, allowing the production of new plant materials enriched or devoid of molecules of pro- and anti-nutritional interest, respectively; historically, the greatest efforts and the most promising results have concerned the obtaining of lines of species of agricultural interest (rice, corn, potato and tomato) in which the vitamin content (A, B, C, E, K) has been increased or accumulated de novo. Subsequently, metabolic engineering found a further field of application in the use of plants as biofactories ("molecular agriculture") for the production of metabolites with high added value and, therefore, of strong industrial interest (pharmaceutical, cosmetics, etc). In this context, ENEA has a long tradition in the field of metabolic engineering, specifically of carotenoids and, more recently, of apocarotenoids: after a general introduction and on the main metabolic engineering strategies for different classes of natural molecules, there will be presented (i) the approaches that led to the creation of potato and tomato lines enriched in ï¢-carotene and total carotenoids (therefore defined as “Golden”); (ii) characterization studies, through the use of omics sciences, of these materials, with particular reference to the accessory effects on metabolism and agronomic traits; (iii) the "molecular farming" strategies that have led to the generation of plants (Nicotiana benthamiana, potatoes and tomatoes) capable of accumulating saffron apocarotenoids. Finally, the research developed in ENEA for the generation and characterization of tomato lines free of anti-nutritional molecules (glycoalkaloids and allergens), produced through genome editing technology, will be presented
Kind: webinars - Date: Jan 28, 2026
Score: 5.98
#3142 - Biosynthesis of Salvia specialized metabolites and biotechnological approaches to increase their production
D’Amelia V, Ruggiero A, Tranchida-Lombardo V, Leone A, Tucci M, Docimo T
Kind: pub - Date: Dec 29, 2020
Score: 3.89
#2508 - PP2A-B′γ modulates foliar trans -methylation capacity and the formation of 4-methoxy-indol-3-yl-methyl glucosinolate in Arabidopsis leaves
Rahikainen M, Trotta A, Alegre S, Pascual J, Vuorinen K, Overmyer K, Moffatt B, Ravanel S, Glawischnig E, Kangasjärvi S
Kind: pub - Date: Apr 05, 2020
Score: 2.49
#2443 - Olive triterpenoids: identification and functional characterization of key biosynthetic genes
Alagna F, Thimmappa R, Reed J, Cultrera NGM, Calderini O, Baldoni L, Osbourn A
Kind: pub - Date: Mar 24, 2020
Score: 1.23
#340 - Silvana Grandillo(personal page)
Main Scientific Interests Development of mapped genetic resources in tomato, with special emphasis given to populations of marker-defined introgression lines (ILs) originating from interspecific crosses, for a more efficient exploitation of the natural biodiversity stored in unadapted germplasm. Current applications of these genetic resources include QTL analyses for fruit quality traits and integrative systems biology and genomic approaches to gain further insights into the networks regulating key fruit metabolic pathways underlying tomato flavour and nutritional quality. Identification and functional characterization of key genes involved in nutritional and merceological quality in pepper. Metabolic engineering of secondary metabolite pathways for the production of health-related compounds.
Kind: personal - Date: Oct 03, 2014
