National Research Council of Italy

Institute of Biosciences and BioResources

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Michele Bellucci

Role: Senior Researcher
Section: Researchers and Technologists
Division: Perugia
Tel: (39) 075-5014815


Senior Researcher at IBBR/CNR



Previous Positions

1994: Istituto Sperimentale per le Colture Foraggere di Lodi (Milano), CRA. Fellowship.

1995 - 1999: Istituto di Ricerche sul Miglioramento Genetico delle Piante Foraggere (IRMGPF), Perugia, CNR. Fellowships.

1999 - 2006: Technician at Institute of Plant Genetics (IGV), Research Division of Perugia, CNR.

2006 - 2020 Researcher at IGV (renamed IBBR from 2013), Research Division of Perugia, CNR.

Since 2020 Senior Researcher at IBBR, Research Division of Perugia, CNR.


Degree: University of Perugia, 1992

PhD: University of Perugia, 2003

Main research topics:

  • Plastid biotechnology

Plastid genetic engineering protocols for tobacco transformation to accumulate recombinant proteins in the chloroplast. The expertise acquired in tobacco plastid transformation has been successfully applied to plastid transformation in sugar beet. Moreover, studies related to recombinant protein stability in the chloroplast have been performed.

  • Non-food crops

Molecular farming: expression in plant (tobacco) of both human enzymes in collaboration with the University of Perugia and protein bioplastics. Studies of hop (Humulus lupulus L.) genetics.

  • Secretory pathway

We investigate diverse aspects of secretory proteins traffic to the endoplasmic reticulum (ER) or the vacuole. We showed the existence of a protein quality control pathway in the ER for degradation directed to the plant vacuole, as well as the existence of new signals and routes (uncoventional protein secretion) for protein vacuolar delivery.


Phone: + 39 075 5014815

Mailing address

Michele Bellucci

Istituto di Bioscienze e BioRisorse (IBBR), CNR,

via Madonna Alta 130,

06128 Perugia, Italy



Selected Publications

(full list available at CNR People)

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