National Research Council of Italy

Institute of Biosciences and BioResources

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Francesca De Marchis

Role: Senior Researcher
Section: Researchers and Technologists
Division: Perugia
Tel: (39) 075-5014810

Date of birth:17/01/1973

Place of work: Institute of Biosciences and Bioresources (IBBR), CNR, via Madonna Alta 130, 06128 Perugia, Italy

Telephone: 0755014810



  • (2023-at present) Senior Researcher at IBBR - CNR, via Madonna Alta 130, 06128 Perugia, Italy
  • (2012-2022) Researcher at IBBR - CNR, via Madonna Alta 130, 06128 Perugia, Italy
  • (2000-2012) research fellow, term contracts at IBBR - CNR, via Madonna Alta 130, 06128 Perugia, Italy. Type of employment or sector: Genetics and Biology and plant biotechnology
  • (1999-2000) Research fellowship at the Experimental Zooprophylactic Institute of Umbria and Marche . Type of employment or sector: production of a vaccine against classical swine fever in plants.


  • (2011-2014) PhD in "Biology and Ecology", University of Perugia
  • (1992-1997) Degree in Biological Sciences, University of Perugia


Genetic, biology and plant biotechnology


- Chloroplast biotechnology

Genetic engineering of tobacco chloroplast in order to accumulate proteins of agronomic, pharmaceutical and industrial interest. Transformation of sugar beet and unicellular alga Chlamydomonas reinhardtii chloroplasts. Studies on the stability of recombinant proteins within the chloroplast and. Exploiting of plastids for the synthesis of vegetable biopolymers of protein origin. Study of alternative selection markers for chloroplast trasformation.

- Non-food crops

Production of proteins for industrial and pharmaceutical use in photosynthetic organisms. Search for vegetable molecules to be used as adjuvants for antibiotic therapy and anti-bacterial biofilm action.

- Protein secretion

Analysis of the different aspects of secretory proteins traffic. Study of the mechanisms that regulate the unconventional trafficking of proteins within the plant cell. Mechanisms that control the synthesis, folding and transport of proteins in the plant cell

Scopus H index: 17 WOS H index 16

Perugia April 2024


Selected Publications

(full list available at CNR People)

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