*

Institute of Biosciences and Bioresources

National Research Council of Italy

Maria Antonietta Ciardiello

Role: Senior Researcher
Section: Researchers and Technologists
Division: Naples
Tel: (39) 081-6132573
E-mail: mariaantonietta.ciardiello@ibbr.cnr.it


Name: Maria Antonietta Ciardiello

Role: Senior Researcher

Date and Place of Birth: 09.11.1960, Postiglione, Italy

Address: Institute of Biosciences and BioResources, Division of Naples, National Research Council, - Via Pietro Castellino, 111 - 80131 Napoli, Italy,

Tel: ++39 081 6132573
E-mail: mariaantonietta.ciardiello@ibbr.cnr.it

Education and Training

1985: Degree in Biological Science at the University "Federico II" of Naples.

  • 1985-1986 - Post-doctoral Fellow at the Department of Organic and Biological Chemistry, University "Federico II" of Naples.
  • 1987-1991: Research fellow as PhD student at the Department of Organic and Biological Chemistry, University "Federico II" of Naples.
  • 1991: PhD in Biochemical Sciences, Department of Organic and Biological Chemistry, Universities of Naples and Bari.
  • 1992-2001: Researcher (5-years ex art. 36 contract) of the Italian National Research Council (CNR), Institute of Protein Biochemistry and Enzymology (IBPE), Naples.
  • 1997: Awarded a three-months EMBO short-term fellowship at the Laboratoire de Biochimie, Université Pierre et Marie Curie, Paris, France.
  • 1997: Awarded a fellowship, in the framework of the CNR Programme "short-term mobility", at the Laboratoire de Biochimie, Université Pierre et Marie Curie, Paris, France.
  • 2001: Permanent position as Researcher at the Italian National Research Council (CNR), Institute of Protein Biochemistry (IBP), Naples.
  • 2014 to date. Researcher at the CNR Institute of Biosciences and BioResources, UOS Naples.

Research Interests

Our research interest is the study of the structural and functional properties of food and environmental proteins and peptides, their physiological role and the impact on human health. New and already known proteins are purified from the natural source by classical biochemical methods and identified by direct amino acid sequencing. The protein characterisation includes the study of the primary, secondary and tertiary structure and post-translational modifications. The functional characterisation includes kinetic studies of enzymatic activities.

Keywards: structure/function of proteins, allergens, nutraceutical peptides, enzymes, food security, functional food, pollen, protein stability.

Current favorite research topics

Identification and purification of new allergenic proteins from the natural food or environmental sources.

  • Structural and immunological characterisation of the molecules under investigation.
  • Analysis of the protein and allergen profile in different foods.
  • Stability of specific allergens under different environmental/experimental conditions, including heat stability and gastrointestinal digestion.
  • Influence of several factors (ripening stage, post-harvest treatments, cultivar, etc) on the variation of the protein and allergen profiles in plant foods.
  • Study of nutraceutical peptides from plant food. Currently our attention is focused on kissper, a peptide isolated from green kiwifruit and showing ion channeling activity in sinthetic membranes, as well as anti-inflammatory effect on human intestinal cells from patients suffering from Crohn’s disease.

Investigation of the protein biological activities, of their possible effects on human health and of their biomedical applications involves the collaboration with research groups having appropriate expertise in the fields of 3D-structure determination, physiology and clinics.

Current main collaborations

Prof. Adriano Mari, Associated Centers for Molecular Allergology (CAAM), Rome

(www.caam-allergy.com/)

Prof. Maksymilian Chruszcz, Department of Chemistry and Biochemistry, University of South Carolina, Columbia, SC, USA

(www.chem.sc.edu/)

Prof. Delia Picone, Department of Chemical Sciences, University of Naples Federico II, Napoli (www.docenti.unina.it/delia.picone)

Dr Silvia Pasquariello, C.R.A. Research Unit on Fruit Trees, Caserta, Italy (http://sito.entecra.it/portale/cra_dati_istituto.php?id=233&lingua=EN)

Prof. Carolina Ciacci, Gastrointestinal Unit, Department of Medicine and Surgery, University of Salerno

(www.unisa.it/dipartimenti/dipmedchi/index)

Publications

Please find the full list of my publications at the following URL:

https://scholar.google.com/citations?user=HmPwLuUAAAAJ&hl=en

 

Selected Publications
(full list available at CNR People)

Page Contents

Related Contents

Other Personal Pages