Institute of Biosciences and Bioresources

National Research Council of Italy

Francesca De Marchis

Role: Researcher
Section: Researchers and Technologists
Division: Perugia
Tel: (39) 075-5014867
E-mail: francesca.demarchis@ibbr.cnr.it

Date of birth: 17/01/1973, Worth Valley (United Kingdom)

(1997) Degree in Biological Sciences, University of Perugia

(2015) PhD in Biology and Ecology, University of Perugia

Work experiences

  • (1999-2000) Fellowship at Zooprophylactic Experimental Institute of Umbria and Marche
  • (2000-2012) Fellowship/research contract at Institute of Plant Genetics (IGV), CNR (today IBBR)
  • (July 2012 - today) Researcher at Institute of Biosciences and Bioresources, Research Division of Perugia, CNR

Main research activities

  • Genetic improvement of crop plants through biotechnological approaches;
  • Production of pharmaceutical and industrial proteins in photosynthetic organisms;
  • Mechanisms regulating protein synthesis, folding and transport inside the plant cell;
  • Chloroplast biology and biotechnology.


Alagna F, Kallenbach M, Pompa A, De Marchis F, Rao R, Baldwin IT, Bonaventure G, Baldoni L. (2015) Olive fruits infested with olive fly (Bactrocera oleae Rossi) larvae respond with an ethylene burst and the emission of specific volatiles. J INTEGR PLANT BIOL 2015. doi: 10.1111/jipb.12343.

Cultrera, F Alagna, R Mariotti, F De Marchis, A Pompa, M Bellucci, L. Baldoni (2014) Isolation and molecular characterization of three acyl carrier protein genes in olive (Olea europaea L.) TREE GENETICS & GENOMES, 10: 895-909

F De Marchis, M Bellucci Plastid Transformation in Sugar Beet: Beta vulgaris. (2014) METHODS MOL BIOL. 1132:367-73

De Marchis F, Bellucci M, Pompa A. (2013). Unconventional pathways of secretory plant proteins from the endoplasmic reticulum to the vacuole bypassing the Golgi complex. PLANT SIGNALING & BEHAVIOR, ISSN: 1559-2316, doi: pii: e25129

De Marchis F, Bellucci M, Pompa A. (2013). Traffic of Human α-Mannosidase in Plant Cells Suggests the Presence of a New Endoplasmic Reticulum-to-Vacuole Pathway without Involving the Golgi Complex.Apr;161(4):1769-82. PLANT PHYSIOLOGY, ISSN: 0032-0889

De Marchis F, Pompa A, Bellucci M (2012). Plastid proteostasis and heterologous protein accumulation in transplastomic plants . PLANT PHYSIOLOGY, vol. 160, p. 571-581, ISSN: 0032-0889

De Marchis F, Pompa A, Mannucci R, Morosinotto T, Bellucci M. (2011). A plant secretory signal peptide targets plastome-encoded recombinant proteins to the thylakoid membrane. PLANT MOLECULAR BIOLOGY, vol. 76, p. 427-441, ISSN: 0167-4412

De Marchis F, Balducci C, Pompa A, Riise Stensland HM, Guaragno M, Pagiotti R, Menghini AR, Persichetti E, Beccari T, Bellucci M. (2011). Human α-mannosidase produced in transgenic tobacco plants is processed in human α-mannosidosis cell lines. PLANT BIOTECHNOLOGY JOURNAL, vol. 9, p. 1061-1073, ISSN: 1467-7644

Pompa A, De Marchis F, Vitale A, Acioni S, Bellucci M (2010). An engineered C-terminal disulfide bond can partially replace the phaseolin vacuolar sorting signal. PLANT JOURNAL, vol. 61, p. 782-791, ISSN: 0960-7412

F. De Marchis, Y. Wang, P. Stevanato, S. Arcioni, M. Bellucci (2009). Genetic transformation of the sugar beet plastome. TRANSGENIC RESEARCH, vol. 18, p. 17-30, ISSN: 0962-8819

O. Foresti, De Marchis F, M. De Virgilio, E. M. Klein, S. Arcioni, M. Bellucci and A. Vitale (2008). Protein Domains Involved in Assembly in the Endoplasmic Reticulum Promote Vacuolar Delivery when Fused to Secretory GFP, Indicating a Protein Quality Control Pathway for Degradation in the Plant Vacuole. MOLECULAR PLANT, vol. 1, p. 1067-1076, ISSN: 1674-2052

De Virgilio M, De Marchis F, Bellucci M, Mainieri D, Rossi M, Benvenuto E, Arcioni S, Vitale A (2008). The human immunodeficiency virus antigen Nef forms protein bodies in leaves of transgenic tobacco when fused to zeolin. JOURNAL OF EXPERIMENTAL BOTANY, vol. 59, p. 2815-2829, ISSN: 1460-2431

BellucciI M, De Marchis F, Arcioni S (2007). Zeolin is a recombinant storage protein that can be used to produce value-added proteins in alfalfa (Medicago sativa L.). PLANT CELL TISSUE AND ORGAN CULTURE, vol. 90, p. 85-91, ISSN: 0167-6857

M. Bellucci, De Marchis F, I. Nicoletti, S. Arcioni (2007). Zeolin is a recombinant storage protein with different solubility and stability properties according to its localization in the endoplasmic reticulum or in the chloroplast. JOURNAL OF BIOTECHNOLOGY, vol. 131, p. 97-105, ISSN: 0168-1656

Marconi G, Albertini E, Barone P, De Marchis F, Lico C, Marusic C, Rutili D, Veronesi F, Porceddu A (2006). In planta mass production of two peptides of the Classical Swine Fever Virus (CSFV) E2 glycoprotein fused to the coat protein of potato virus X. BMC BIOTECHNOLOGY, ISSN: 1472-6750

Bellucci M, De Marchis F, Mannucci R, Bock R, Arcioni S (2005). Cytoplasm and chloroplasts are not suitable subcellular locations for {beta}-zein accumulation in transgenic plants. JOURNAL OF EXPERIMENTAL BOTANY, vol. 56, p. 1205-1212, ISSN: 1460-2431

Cappelli K, Porceddu A, Verini-Supplizi A, Capomaccio S, De Marchis F, FalcinelliI M, Gaiti A, Silvestrelli M (2005). cDNA AFLP-based techniques for studying transcript profiles in horses. RESEARCH IN VETERINARY SCIENCE, vol. 79, p. 105-112, ISSN: 0034-5288

Bellucci M, Ederli L, De Marchis F, Pasqualini S, Arcioni S (2004). Transformation of Lotus corniculatus plants with E. coli asparagine synthetase A: effect on nitrogen assimilation and plant development. PLANT CELL TISSUE AND ORGAN CULTURE, vol. 78, p. 139-150, ISSN: 0167-6857

Mainieri D, Rossi M, Archinti M, Bellucci M, De Marchis F, Vavassori S, Pompa A, Arcioni S, Vitale A (2004). Zeolin. A new recombinant storage protein constructed using maize gamma-zein and bean phaseolin. PLANT PHYSIOLOGY, vol. 136, p. 3447-3456, ISSN: 0032-0889

M. Bellucci De Marchis F, R. Mannucci, S. Arcioni (2003). Jellyfish green fluorescent protein as a useful reporter in Medicago sativa for transient expression and stable transformation. PLANT CELL REPORTS, vol. 22, p. 328-337, ISSN: 0721-7714

De Marchis F, Bellucci M, Arcioni S (2003). Measuring gene flow from two birdsfoot trefoil (Lotus corniculatus) field trials using transgenes as tracer markers. MOLECULAR ECOLOGY, vol. 12, p. 1681-1685, ISSN: 0962-1083

Pasqualini S, Batini P, Ederli L, Porceddu A, Piccioni C, De Marchis F, Antonielli M (2001). Effects of short-term ozone fumigation on tabacco plants: response of the scavenging system and expression of the glutathione reductase. PLANT, CELL & ENVIRONMENT, vol. 24, p. 245-252, ISSN: 1365-3040


Selected Publications
(full list available at CNR People)

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